12 weeks ultrasound

The 12 weeks ultrasound examination can be done from 11 weeks 4 days to 13 weeks 6 days. The scan is usually performed transabdominally.  Sometimes, it may be necessary to do the scan transvaginally.
The aims of the 12 weeks ultrasound are:

  • To date the pregnancy accurately  (if  this has not been done yet).
  • To diagnose the type of  twin (or other multiple) pregnancy. It is important to know whether each twin has its own placenta, or whether they share a common placenta.  If they share a placenta, it is advisable to monitor the pregnancy more closely.
  • To check whether the baby is growing and developing normally. Some  major abnormalities can be visible at 12 weeks, but it is much better to have an ultrasound examination at  20 weeks to exclude structural  abnormalities.
  • To assess the risks of Down’s syndrome and other chromosomal abnormalities.
    Your  individual risk for this pregnancy is calculated by taking into account your age, measurement of hormones in your blood and the ultrasound findings.

Personal risk of Down syndrome

Most babies are normal. On the other hand, each woman, regardless her age, has a small risk of having a baby with a physical or mental handicap.

The only way of knowing for certain whether a baby has a chromosomal anomaly or not, is to do an invasive procedure such as a chorionic villus sample or amniocentesis. These procedures have a risk of about 1/300 to cause a miscarriage. The most accurate, but most expensive, screening test for Down syndrome is non-invasive testing of fetal DNA.

The ultrasound examination between 11 and 13 weeks also evaluates the risk of Down syndrome, which depends on:

  • your age,
  • the level of two hormones (free ß-hCG and PAPP-A) in your blood and
  • ultrasound findings: especially the thickness of fluid behind the baby’s neck (nuchal translucency thickness) and possible structural anomalies. To refine the risk assessment, the nasal bone, heart rate and blood flow in a vein between the umbilical cord can also be evaluated.

After the ultrasound evaluation, the risk of Down syndrome and other chromosomal anomalies (trisomy 13 and 18) will be discussed with you. Based on the risk assessment you can decide whether you would like invasive testing (by mean of a chorionic villus sample or amniocentesis) (usually if the risk is higher than 1:300) or non-invasive DNA testing.

The risk assessment remains a screening test. Under optimal circumstances the test would detect 90% of babies with Down syndrome, with a 5% chance of a false positive test. Optimal conditions include a blood test done between 8 to 10 weeks and an ultrasound performed by someone with the specific training and whose ultrasound examinations are subject to independent quality control. (Although the blood tests are done previously, their results are only taken into account once the ultrasound results are available.)

An ultrasound at 20 weeks is also recommended to exclude physical problems.

Your husband is very welcome to join you during the ultrasound scan. Another friend or your parents (or in-laws) are also welcome. Keep in mind, though, that too many people can make it difficult for you and your husband to focus if something specific needs to be explained. To bring small children along is usually boring for the child and distracting for yourself.



Fetal Medicine Foundation – the mother of all 12 weeks ultrasound screening programmes

 Where Down syndrome comes from – information from the Down Syndrome Association of South Africa

Information on the Down syndrome screening test

What the ultrasound images look like: (images from the Fetal Medicine Foundation)


Nuchal translucency measurement - 12 weeks ultrasound

Nuchal translucency measurement

Nasal bone - 12 weeks ultrasound, Dr Lou Pistorius

Nasal bone

Blood flow through ductus venosus - 12 weeks ultrasound, Dr Lou Pistorius

Blood flow through ductus venosus